how you would use JCVI-syn3.0 to investigate basic cellular biology or to use the organism to learn how to make a better cell for some research, medical, or industrial purpose.

https://lh4.googleusercontent.com/j9x5uLpBc5nUMJaQQB0kdwVeMhL0e5jOBxfjQDAbaRMdOsaaGt98J9b6oH7egR9VFs-eyNfJlOkg26gTEGhBU4WgJ2QntBTE4vAaNMdVINk8Bx249llGrTZpp0nm5g8L

If I have a opportunity to use the JCVI-syn3.0 I hope I can use this minimal cell to have a function of cleaning the air pollution. Due to the heavy air pollution in Asia these day and cause the seriously health issue. i think this will be a great idea to create the JCVI-syn3.0 to have the function of cleaning the air pollution and catch the PM2.5.

In previous classes, George Church has talked about work done in his lab to do grand scale genome engineering of E. coli to alter its genetic code. While there are similarities with how his lab engineers E. coli with how the JCVI engineers mycoplasmas, what is the fundamental difference or differences?

<aside> 🧬 JCVI research group – bottom up approach

</aside>

-novo reduced genome using gene synthesis technology.

-Transposon mutagenesis – transferred to a host organism

-Using of yeast as chassis and then to a bacteria

<aside> 🧬 George Church group – top down approach

</aside>

-multiplex automated genome engineering

-MAGE as a way

-CAGE technology bacterial conjugation

-Using bacteria like chassis and then other

bacteria to complete genome.

https://lh4.googleusercontent.com/NRtk3rDQDfNyC0-5Y5hFQmP82hIF8AloRA5ur7-JV0kilCTmjWDTS8x4KTMo5x3ZSVPD1OgdZ-spmij4uaf1J65qbMESE6G2T_QNhJa1IMyfzndj2zOlBcPWBPrUz0EK

https://lh6.googleusercontent.com/xLbSf95IWSGP0bXIcA3ImL4uICFun5XFzm12vbYMocKJABtIq6okmo6JC59P3g2u1btptmIfr-FdQGzKRIcZrgL5dTzUnVkiKDvA23IgbXnRMs2vPQ0rteu2At0zHaZF