Vitamin C (ascorbic acid)

used for hydroxylation

hydroxylates proline and lysine in collagen and elastin

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absorption of iron in GI tract

main antioxidant in the GI system

Deficiency -

• Scurvy
• Bleeding from hair follicles and gums

Toxicity -

• N, V, D, fatigue, sleep problem;
• may increase iron toxicity
• large doses of Vit. C can give false negative stool guaiac results and are associated with diarrhea and abdominal bloating;
• may also relate to calcium oxalate nephrolithiasis