B1 (Thiamine)

• as thiamine pyrophosphate TPP ( do not confuse with TTP, nucleotide)

required for -

1. Branched chain amino acid dehydrogenase
2. Alpha-ketogluterate dehydrogenase (TCA cycle)
3. Transketolase (HMP shunt)
4. Pyruvate dehydrogenase

"B for ATP"

Three Enzymes requiring five cofactors including Thiamine

1. Branched chain alpa-ketoacid dehydrogenase, in amino acid catabolism; MSUD when deficient
2. Pyruvate dehydrogenase, in glucose metabolism
3. Alpha-ketoglutarate dehydrogenase, in TCA cycle

"Tender Loving Care For Nancy"

• Thiamine pyrophosphate
• Lipoate
• Coenzyme A
• FAD
• NAD