Related to GI infection
Giardia lamblia
Entamoeba histolytica
Two forms: cyst (infective form) and trophozoite stage (invasive disease)
The E histolytica galactose/N-acetyl-D-galactosamine (Gal/GalNAc) lectin is an adhesion protein complex that sustains tissue invasion.
Right lobe > Left lobe of liver (because right lobe portal laminar blood flow is supplied by superior mesenteric vein, where as the left lob portal blood flow is supplied by the splenic vein.)
Amoebic Liver Abscess
Pleuropulmonary infection is the most common complication
Recent travel to endemic areas
Fever + abd pain < 14 days, diarrhea in < 1/3 of patients
Labs:
High AST and ALP
Stool Ag
EIA serology
USG