Drug causes of pulmonary fibrosis

'CHARTS on PC' for upper zone fibrosis:

• C- Coal Worker's Pneumoconiosis

• H- Histiocytosis (Langerhans cell) and Hypersensitivity Pneumonitis (mid to upper zone)

• A- Ankylosing Spondylitis (late complication), ABPA, EAA

• R- Radiation

• T- TB

• S- Silicosis and Sarcoidosis

• P- PJP - Pneumocystis (subacute/chronic)

• C - Cystic fibrosis

‘RAIDS’ For lower zone fibrosis:

• R - rheumatoid arthritis (RA-ILD is basal and peripheral)
• A - asbestosis (lower-lobe, subpleural fibrosis); Aspiration (recurrent) → basal fibrosis
• I - IPF (idiopathic pulmonary fibrosis)
• D - drug induced (e.g., amiodarone, methotrexate, nitrofurantoin, bleomycin)
• S - systemic sclerosis; and Sjögren’s, MCTD