Predecible, consistente y responsive (abajo)
Columns, gutter and margin.
A multi-column grid focuses on splitting the page into more than one vertical column, with a gutter. Traditionally for the screen, this has manifested itself in a 12-column grid, often set at 960px wide with 60px columns and 20px gutters.
Typography lessons-how to create grids for screens
4pt, 8pt y más:
Source: IDF