Henoch-Schönlein Purpura (HSP)

more common in children

GIT -  colicky pain (due to local vasculitis), bleeding, intussusceptions

Skin -  palpable purpura distributed symmetrically over the lower legs, buttocks, and arms

Joint-  arthralgia, most commonly affect the knees and ankles

Renal - 20%-50% of children; may occur as late as 4-6 wks afer onset of the illness

presents with hematuria >>similar to IgA nephropathy due to IgA-mediated leukocytoclastic vasculitis

however, do not test IgA levels which is not reliable

Dx

• Normal (or increased) platelet count & WBC
• ESR may be elevated, anemia
• normal coagulation studies
• Normal or raised creatinine
• Increased IgA, IgM