Blood and WBCs in stool

Salmonella: contaminated poultry and eggs; more common in patients with SCD and achlorhydria

Campylobacter jejuni: most common cause, associated with raw or undercooked meats; abdo pain (may mimic appendicitis) and bloody diarrhea; rarely associated with GBS

E. coli  EHEC O157:H7 -- associated with contaminated vegetarian food, such as German outbreak lined to bean sprouts, undercooked hamburger meat; hemolytic uremic syndrome (HUS)

(maybe no WBCs)

Certain patients may benefit from early plasma exchange or from use of anti-complement monoclonal antibodies.

EIEC

Shigella: 2nd most common association with HUS; associated with contaminated food or water, esp. during travel outside the US

Vibrio parahaemolyticus: shellfish and cruise ships

Vibrio vulnificus: raw shellfish, h/o liver disease, iron overload and bullous skin lesions --> cellulitis, sepsis

Yersinia enterocolitica: high affinity for iron, hemochromatosis, blood transfusions; can mimic appendicitis or Chron's disease

tends to infect the cecum rather than distal colon

Clostridium difficile: the cause of pseudomembranous colitis related to previous antibiotic use or use of antiperistaltic drugs;  white and red cells in stool

Clostridium botulinum :   infected canned foods

Clostridium perfringens:  meats taht have been contaminated with spores by being unrefrigerated

The major protozoan associated with blood in the stool is Entamoeba histolytica.

No Blood and WBCs in stool