Ectopic

Implantation of a fertilized ovum outside the uterus results in an ectopic pregnancy

Epidemiology

Risk factors (anything slowing the ovum's passage to the uterus)

Women who are stable are typically investigated and managed in an early pregnancy assessment unit. If a woman is unstable then she should be referred to the emergency department.

Investigation

β-hCG

The investigation of choice for ectopic pregnancy is a transvaginal ultrasound.

Management

There are 3 ways to manage ectopic pregnancies. And the following criteria can help to guide you on which method your patient will be able to have.

Expectant management Medical management Surgical management
Size <35mm Size <35mm Size >35mm
Unruptured Unruptured Can be ruptured
Asymptomatic No significant pain Pain
No fetal heartbeat No fetal heartbeat Visible fetal heartbeat
hCG <1,000IU/L hCG <1,500IU/L hCG >5,000IU/L
Compatible if another intrauterine pregnancy Not suitable if intrauterine pregnancy Compatible with another intrauterine pregnancy
Expectant management involves closely monitoring the patient over 48 hours and if B-hCG levels rise again or symptoms manifest intervention is performed. Medical management involves giving the patient methotrexate and can only be done if the patient is willing to attend follow-up. Surgical management can involve salpingectomy or salpingotomy
Salpingectomy is first-line for women with no other risk factors for infertility
Salpingotomy should be considered for women with risk factors for infertility such as contralateral tube damage
• around 1 in 5 women who undergo a salpingotomy require further treatment (methotrexate and/or a salpingectomy)