Hyposplenism e.g. post-splenectomy, coeliac disease (occurs in around 30% of coeliac patients)

• target cells
• Howell-Jolly bodies
• Pappenheimer bodies
• siderotic granules
• acanthocytes

Iron-deficiency anaemia

• target cells
• 'pencil' poikilocytes
• if combined with B12/folate deficiency a 'dimorphic' film occurs with mixed microcytic and macrocytic cells

Myelofibrosis

• 'tear-drop' poikilocytes

Intravascular haemolysis

• schistocytes

Blood film with schistocytes highlighted

Megaloblastic anaemia

• hypersegmented neutrophils

Hyposplenisme.g. post-splenectomy

• target cells