Anion Gap

ABG analysis

Metabolic acidosis defined as a serum HCO3 <22 mEq/L that is not generated by respiratory alkalosis

Renal Buffer

Urinary acid excretion occurs primarily in the form of NH4+ and titratable acids (H2PO4-).

In metabolic acidosis, urinary pH decreases due to increased excretion of free H+, NH4+, and H2PO4-.

Bicarbonate is completely reabsorbed from the tubular fluid in acidotic states.