Overview

Metabolic Acidosis

Anion Gap

Anion-Gap Formula Caveats:

• Albumin Correction. Add 2.5 to AG value for every 10 g/L drop in Albumin. This is because Albumin is an unmeasured anion and so when it is lost, to maintain isoelectricity we will retain anions such as chloride and bicarbonate. This makes our AG falsely low and so we need to add the 2.5 value.

High Anion Gap Metabolic Acidosis

Harrison’s Textbook of IM

HAGMA.pdf