We've tested accessibility on this platform with this content and found it plays well with screenreaders. However, we make no promises here: if you have a student requiring accommodation in your class you should determine the specific needs of that student and determine your own testing protocol.
Our accessibility approach is to write accessible pages in Notion (e.g. add descriptive image captions, use descriptive links) using standard Notion features, and for the vast majority of students — even those with accommodations — the live online version is the best experience. For students that require a downloadable offline version of the materials, we recommend HTML export as we've found the PDF export does not play well with screenreaders. (Seriously, do not post PDF exports if you have accessibility concerns)