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💡 Far more than a ‘molecule’ associated with being a man, testosterone is literally the lifeblood and the foundation of all things related to male health.
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Facts
- Low testosterone baseline constantly declines and the cutoff of 300 is far below what it should be
- 25% of men are type I or II —> believed to be underestimated and under-reported
- Men 60 years ago had 3X the level of testosterone of men today
- DHT is especially important in the brain as it promotes neurogenesis
- Vast majority of testosterone in human males is produced by Leydig cells in the testes, with about 5% produced under the control of the HPA axis
- Gynecomastia (breast tissue growth) more commonly caused by high, prolactin rather than estrogen.
- Aromatase is an enzyme that testosterone into estrogen estrogen. Aromatase is incredibly important for cognitive function, blood flow, spermatogenesis, testiclular health
- Too much exogenous testosterone can cause Leydig cell die off in the testes
Quantification
- Albumin bound testosterone is still very bioavailable
- Low Testosterone can also be too high cortisol
Tips
- Avoid chronic cardio
- Long rests
- Magnesium + zinc (for heavy sweaters)