We created a summary of the meeting using OpenAI's Whisper and ChatGPT from the audio data. However, due to the accuracy of the speech recognition and the limitation of ChatGPT's summary to 8196 tokens, the minutes may not be entirely accurate (we have also made minor manual adjustments). Please keep this in mind as a reference for the minutes.

To begin, thank you for attending today's meeting. My name is Ken Nakae, and I am a special associate professor at the National Institute of Natural Sciences and the Institute of Physiology. This research meeting began as the Computational Neuroscience Research Meeting, co-hosted by Yada-san from Hiroshima University.

This research meeting is supported by funding from the Center for the Study of Behavioral Biology and the Center for Life Creation Exploration, which are involved in academic transformation. There are many leading researchers in Japan in the field of Computational Neuroscience, such as Professors Amari, Kawato, and Doi. While my specialty is data science, I am also interested in Computational Neuroscience.

Recently, there has been increased attention on computer psychometrics (psychiatry), and it is believed that the computational approach can be applied to neurodegenerative diseases such as Alzheimer's and Parkinson's. In addition, a government-led brain science project is underway, and research to meet future medical needs is actively being discussed.

Therefore, the research areas that we should focus on are promoting computational research both domestically and internationally, such as the computational neuroscience approach to psychiatric and neurodegenerative diseases and the development of new therapies.

At this research meeting, Yada-san will introduce his research using AI for the diagnosis and prediction of dementia. We will also discuss how advances in data science and mathematical science have responded to the needs of the country and society, as well as future prospects.

In Parkinson's disease research, brain oscillations are being studied, but the relationship between information processing and the disease is not yet clear. Researchers have proposed various hypotheses. This presentation will introduce simulations of the oscillations and their occurrence in Parkinson's disease.

First, it has been shown that abnormal beta oscillations occur in the basal ganglia in Parkinson's disease. In addition, it has been suggested that slow gamma and beta oscillations involved in movement may be related to the pathophysiology of Parkinson's disease. These oscillations are associated with different populations of neurons and are believed to play an important role in the selection and suppression of movement.

In the current simulation model, only constituent suggestions have been made. However, there are still unknowns about information processing, and further challenges remain.

In the future, the reproduction of gamma oscillations by simulation may be useful for individual treatments of Parkinson's and Alzheimer's diseases. In addition, considering that neurons and networks show different interactions depending on the frequency band, it may be a realistic challenge to investigate the effects of deep brain stimulation on brain activity by simulation. We will continue to conduct further research using more detailed models to obtain more accurate results.

In addition, Lüthiénsen-Sensei's presentation, titled "The Brain as a Complex Empire System," explained the technology of neural system networks, gene expression, and neural activity. Topics such as Alzheimer's disease and mental illness were also discussed, and recent papers on brain Alzheimer's were mentioned.

For the next research meeting, online participants are expected to use the same link. Those who wish to participate on-site were asked to contact us. Finally, we expressed our gratitude for the presentation and the lively questions, and showed our enthusiasm for continuing our research.

Our contact information is available on the mailing list, Google group, website, and Twitter account. We welcome the participation of many people in the upcoming events, and note that the next two presentations will be in English.

Finally, we called for a symposium on big data analysis at the Neuroscience Society and to submit the results to a journal. The research meeting ended for a break, and discussions resumed. Participants expressed their gratitude, and the research meeting ended successfully.